Cargando…
Contribution of Amino Acid Region 659−663 of Factor Va Heavy Chain to the Activity of Factor Xa within Prothrombinase,
[Image: see text] Factor Va, the cofactor of prothrombinase, is composed of heavy and light chains associated noncovalently in the presence of divalent metal ions. The COOH-terminal region of the heavy chain contains acidic amino acid clusters that are important for cofactor activity. In this work,...
| Autores principales: | , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2010
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946813/ https://www.ncbi.nlm.nih.gov/pubmed/20722419 http://dx.doi.org/10.1021/bi101097t |