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The Structure of (CENP-A/H4)(2) Reveals Physical Features that Mark Centromeres

Centromeres are specified epigenetically, and the histone H3 variant, CENP-A, is assembled into the chromatin of all active centromeres1. Divergence from H3 raises the possibility that CENP-A generates unique chromatin features to physically mark centromere location. The crystal structure of the sub...

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Detalles Bibliográficos
Autores principales: Sekulic, Nikolina, Bassett, Emily A., Rogers, Danielle J., Black, Ben E.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946842/
https://www.ncbi.nlm.nih.gov/pubmed/20739937
http://dx.doi.org/10.1038/nature09323