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Axonal-Transport-Mediated Gene Transduction in the Interior of Rat Bone

BACKGROUND: Gene transduction has been considered advantageous for the sustained delivery of proteins to specific target tissues. However, in the case of hard tissues, such as bone, local gene delivery remains problematic owing to anatomical accessibility limitations of the target sites. METHODOLOGY...

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Detalles Bibliográficos
Autores principales: Okabayashi, Toshitaka, Nakanishi, Kuniaki, Tsuchihara, Toyokazu, Arino, Hiroshi, Yoshihara, Yasuo, Tominaga, Susumu, Uenoyama, Maki, Suzuki, Shinya, Asagiri, Masataka, Nemoto, Koichi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946924/
https://www.ncbi.nlm.nih.gov/pubmed/20927397
http://dx.doi.org/10.1371/journal.pone.0013034