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Desynchronization of Neocortical Networks by Asynchronous Release of GABA at Autaptic and Synaptic Contacts from Fast-Spiking Interneurons

Networks of specific inhibitory interneurons regulate principal cell firing in several forms of neocortical activity. Fast-spiking (FS) interneurons are potently self-inhibited by GABAergic autaptic transmission, allowing them to precisely control their own firing dynamics and timing. Here we show t...

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Detalles Bibliográficos
Autores principales: Manseau, Frédéric, Marinelli, Silvia, Méndez, Pablo, Schwaller, Beat, Prince, David A., Huguenard, John R., Bacci, Alberto
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946936/
https://www.ncbi.nlm.nih.gov/pubmed/20927409
http://dx.doi.org/10.1371/journal.pbio.1000492