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Involvement of F1296 and N1303 of CFTR in induced-fit conformational change in response to ATP binding at NBD2

The chloride ion channel cystic fibrosis transmembrane conductance regulator (CFTR) displays a typical adenosine trisphosphate (ATP)-binding cassette (ABC) protein architecture comprising two transmembrane domains, two intracellular nucleotide-binding domains (NBDs), and a unique intracellular regul...

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Detalles Bibliográficos
Autores principales: Szollosi, Andras, Vergani, Paola, Csanády, László
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947058/
https://www.ncbi.nlm.nih.gov/pubmed/20876359
http://dx.doi.org/10.1085/jgp.201010434