CD11c depletion severely disrupts Th2 induction and development in vivo

Although dendritic cells (DCs) are adept initiators of CD4(+) T cell responses, their fundamental importance in this regard in Th2 settings remains to be demonstrated. We have used CD11c–diphtheria toxin (DTx) receptor mice to deplete CD11c(+) cells during the priming stage of the CD4(+) Th2 respons...

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Detalles Bibliográficos
Autores principales: Phythian-Adams, Alexander T., Cook, Peter C., Lundie, Rachel J., Jones, Lucy H., Smith, Katherine A., Barr, Tom A., Hochweller, Kristin, Anderton, Stephen M., Hämmerling, Günter J., Maizels, Rick M., MacDonald, Andrew S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947067/
https://www.ncbi.nlm.nih.gov/pubmed/20819926
http://dx.doi.org/10.1084/jem.20100734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947067/
https://www.ncbi.nlm.nih.gov/pubmed/20819926
http://dx.doi.org/10.1084/jem.20100734

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