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Addiction-like reward dysfunction and compulsive eating in obese rats: Role for dopamine D2 receptors
We found that development of obesity was coupled with the emergence of a progressively worsening brain reward deficit. Similar changes in reward homeostasis induced by cocaine or heroin is considered a critical trigger in the transition from casual to compulsive drug-taking. Accordingly, we detected...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947358/ https://www.ncbi.nlm.nih.gov/pubmed/20348917 http://dx.doi.org/10.1038/nn.2519 |