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SPG20 Protein Spartin Is Recruited to Midbodies by ESCRT-III Protein Ist1 and Participates in Cytokinesis

Hereditary spastic paraplegias (HSPs, SPG1-46) are inherited neurological disorders characterized by lower extremity spastic weakness. Loss-of-function SPG20 gene mutations cause an autosomal recessive HSP known as Troyer syndrome. The SPG20 protein spartin localizes to lipid droplets and endosomes,...

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Detalles Bibliográficos
Autores principales: Renvoisé, Benoît, Parker, Rell L., Yang, Dong, Bakowska, Joanna C., Hurley, James H., Blackstone, Craig
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947466/
https://www.ncbi.nlm.nih.gov/pubmed/20719964
http://dx.doi.org/10.1091/mbc.E09-10-0879