ZFP36L1 Negatively Regulates Erythroid Differentiation of CD34+ Hematopoietic Stem Cells by Interfering with the Stat5b Pathway

ZFP36L1 is a member of a family of CCCH tandem zinc finger proteins (TTP family) able to bind to AU-rich elements in the 3′-untranslated region of mRNAs, thereby triggering their degradation. The present study suggests that such mechanism is used during hematopoiesis to regulate differentiation by p...

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Detalles Bibliográficos
Autores principales: Vignudelli, Tatiana, Selmi, Tommaso, Martello, Andrea, Parenti, Sandra, Grande, Alexis, Gemelli, Claudia, Zanocco-Marani, Tommaso, Ferrari, Sergio
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947470/
https://www.ncbi.nlm.nih.gov/pubmed/20702587
http://dx.doi.org/10.1091/mbc.E10-01-0040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947470/
https://www.ncbi.nlm.nih.gov/pubmed/20702587
http://dx.doi.org/10.1091/mbc.E10-01-0040

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