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Different Localizations and Cellular Behaviors of Leiomodin and Tropomodulin in Mature Cardiomyocyte Sarcomeres

Leiomodin (Lmod) is a muscle-specific F-actin–nucleating protein that is related to the F-actin pointed-end–capping protein tropomodulin (Tmod). However, Lmod contains a unique ∼150-residue C-terminal extension that is required for its strong nucleating activity. Overexpression or depletion of Lmod...

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Detalles Bibliográficos
Autores principales: Skwarek-Maruszewska, Aneta, Boczkowska, Malgorzata, Zajac, Allison L., Kremneva, Elena, Svitkina, Tatyana, Dominguez, Roberto, Lappalainen, Pekka
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947471/
https://www.ncbi.nlm.nih.gov/pubmed/20685966
http://dx.doi.org/10.1091/mbc.E10-02-0109