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Osmoprotective Transcription Factor NFAT5/TonEBP Modulates Nuclear Factor-κB Activity

Tonicity-responsive binding-protein (TonEBP or NFAT5) is a widely expressed transcription factor whose activity is regulated by extracellular tonicity. TonEBP plays a key role in osmoprotection by binding to osmotic response element/TonE elements of genes that counteract the deleterious effects of c...

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Detalles Bibliográficos
Autores principales: Roth, Isabelle, Leroy, Valérie, Kwon, H. Moo, Martin, Pierre-Yves, Féraille, Eric, Hasler, Udo
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947481/
https://www.ncbi.nlm.nih.gov/pubmed/20685965
http://dx.doi.org/10.1091/mbc.E10-02-0133