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Quantitative Phosphoproteomics of Proteasome Inhibition in Multiple Myeloma Cells
BACKGROUND: The proteasome inhibitor bortezomib represents an important advance in the treatment of multiple myeloma (MM). Bortezomib inhibits the activity of the 26S proteasome and induces cell death in a variety of tumor cells; however, the mechanism of cytotoxicity is not well understood. METHODO...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947515/ https://www.ncbi.nlm.nih.gov/pubmed/20927383 http://dx.doi.org/10.1371/journal.pone.0013095 |