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Interferon Alpha Induces Establishment of Alphaherpesvirus Latency in Sensory Neurons In Vitro

BACKGROUND: Several alphaherpesviruses, including herpes simplex virus 1 (HSV-1) and pseudorabies virus (PRV), establish lifelong latency in neurons of the trigeminal ganglion (TG). Although it is thought that efficient establishment of alphaherpesvirus latency is based on a subtle interplay between...

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Detalles Bibliográficos
Autores principales: De Regge, Nick, Van Opdenbosch, Nina, Nauwynck, Hans J., Efstathiou, Stacey, Favoreel, Herman W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947521/
https://www.ncbi.nlm.nih.gov/pubmed/20927329
http://dx.doi.org/10.1371/journal.pone.0013076