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Delayed Onset of Experimental Autoimmune Encephalomyelitis in Olig1 Deficient Mice

BACKGROUND: Olig1 is a basic helix-loop-helix (bHLH) transcription factor that is essential for oligodendrogenesis and efficient remyelination. However, its role in neurodegenerative disorders has not been well-elucidated. METHODOLOGY/PRINCIPAL FINDINGS: Here we investigated the effects of Olig1 def...

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Detalles Bibliográficos
Autores principales: Guo, Xiaoli, Harada, Chikako, Namekata, Kazuhiko, Mitamura, Yoshinori, Yoshida, Hiroshi, Matsumoto, Yoh, Harada, Takayuki
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947525/
https://www.ncbi.nlm.nih.gov/pubmed/20927333
http://dx.doi.org/10.1371/journal.pone.0013083