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ADF/Cofilin-Mediated Actin Dynamics Regulate AMPA Receptor Trafficking during Synaptic Plasticity

Dendritic spines undergo actin-based growth and shrinkage during synaptic plasticity. The actin depolymerizing factor (ADF)/cofilin family of actin-associated proteins plays important roles in spine plasticity. Elevated ADF/cofilin activities often lead to reduced spine size and immature spine morph...

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Detalles Bibliográficos
Autores principales: Gu, Jiaping, Lee, Chi Wai, Fan, Yanjie, Komlos, Daniel, Tang, Xin, Sun, Chicheng, Yu, Kuai, Hartzell, H Criss, Chen, Gong, Bamburg, James R., Zheng, James Q.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947576/
https://www.ncbi.nlm.nih.gov/pubmed/20835250
http://dx.doi.org/10.1038/nn.2634