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Systems Biology of Coagulation Initiation: Kinetics of Thrombin Generation in Resting and Activated Human Blood

Blood function defines bleeding and clotting risks and dictates approaches for clinical intervention. Independent of adding exogenous tissue factor (TF), human blood treated in vitro with corn trypsin inhibitor (CTI, to block Factor XIIa) will generate thrombin after an initiation time (T(i)) of 1 t...

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Detalles Bibliográficos
Autores principales: Chatterjee, Manash S., Denney, William S., Jing, Huiyan, Diamond, Scott L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947981/
https://www.ncbi.nlm.nih.gov/pubmed/20941387
http://dx.doi.org/10.1371/journal.pcbi.1000950