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Phylogenetic Approach Reveals That Virus Genotype Largely Determines HIV Set-Point Viral Load

HIV virulence, i.e. the time of progression to AIDS, varies greatly among patients. As for other rapidly evolving pathogens of humans, it is difficult to know if this variance is controlled by the genotype of the host or that of the virus because the transmission chain is usually unknown. We apply t...

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Detalles Bibliográficos
Autores principales: Alizon, Samuel, von Wyl, Viktor, Stadler, Tanja, Kouyos, Roger D., Yerly, Sabine, Hirschel, Bernard, Böni, Jürg, Shah, Cyril, Klimkait, Thomas, Furrer, Hansjakob, Rauch, Andri, Vernazza, Pietro L., Bernasconi, Enos, Battegay, Manuel, Bürgisser, Philippe, Telenti, Amalio, Günthard, Huldrych F., Bonhoeffer, Sebastian
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947993/
https://www.ncbi.nlm.nih.gov/pubmed/20941398
http://dx.doi.org/10.1371/journal.ppat.1001123