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Pathogenic Bacteria Target NEDD8-Conjugated Cullins to Hijack Host-Cell Signaling Pathways

The cycle inhibiting factors (Cif), produced by pathogenic bacteria isolated from vertebrates and invertebrates, belong to a family of molecules called cyclomodulins that interfere with the eukaryotic cell cycle. Cif blocks the cell cycle at both the G(1)/S and G(2)/M transitions by inducing the sta...

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Detalles Bibliográficos
Autores principales: Jubelin, Grégory, Taieb, Frédéric, Duda, David M., Hsu, Yun, Samba-Louaka, Ascel, Nobe, Rika, Penary, Marie, Watrin, Claude, Nougayrède, Jean-Philippe, Schulman, Brenda A., Stebbins, C. Erec, Oswald, Eric
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947998/
https://www.ncbi.nlm.nih.gov/pubmed/20941356
http://dx.doi.org/10.1371/journal.ppat.1001128