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Cdc20 Is Critical for Meiosis I and Fertility of Female Mice

Chromosome missegregation in germ cells is an important cause of unexplained infertility, miscarriages, and congenital birth defects in humans. However, the molecular defects that lead to production of aneuploid gametes are largely unknown. Cdc20, the activating subunit of the anaphase-promoting com...

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Detalles Bibliográficos
Autores principales: Jin, Fang, Hamada, Masakazu, Malureanu, Liviu, Jeganathan, Karthik B., Zhou, Wei, Morbeck, Dean E., van Deursen, Jan M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947999/
https://www.ncbi.nlm.nih.gov/pubmed/20941357
http://dx.doi.org/10.1371/journal.pgen.1001147