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Cdc20 Is Critical for Meiosis I and Fertility of Female Mice
Chromosome missegregation in germ cells is an important cause of unexplained infertility, miscarriages, and congenital birth defects in humans. However, the molecular defects that lead to production of aneuploid gametes are largely unknown. Cdc20, the activating subunit of the anaphase-promoting com...
Autores principales: | Jin, Fang, Hamada, Masakazu, Malureanu, Liviu, Jeganathan, Karthik B., Zhou, Wei, Morbeck, Dean E., van Deursen, Jan M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947999/ https://www.ncbi.nlm.nih.gov/pubmed/20941357 http://dx.doi.org/10.1371/journal.pgen.1001147 |
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