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Identification of Thioaptamer Ligand against E-Selectin: Potential Application for Inflamed Vasculature Targeting

Active targeting of a drug carrier to a specific target site is crucial to provide a safe and efficient delivery of therapeutics and imaging contrast agents. E-selectin expression is induced on the endothelial cell surface of vessels in response to inflammatory stimuli but is absent in the normal ve...

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Detalles Bibliográficos
Autores principales: Mann, Aman P., Somasunderam, Anoma, Nieves-Alicea, René, Li, Xin, Hu, Austin, Sood, Anil K., Ferrari, Mauro, Gorenstein, David G., Tanaka, Takemi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948018/
https://www.ncbi.nlm.nih.gov/pubmed/20927342
http://dx.doi.org/10.1371/journal.pone.0013050