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Identification of a quality control mechanism for mRNA 5’-end capping

The 7-methylguanosine cap structure at the 5′-end of eukaryotic mRNAs is a critical determinant of their stability and translational efficiency1–3. It is generally believed that 5’-end capping is a constitutive process that occurs during mRNA maturation and lacks the need for a quality control mecha...

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Detalles Bibliográficos
Autores principales: Jiao, Xinfu, Xiang, Song, Oh, ChanSeok, Martin, Charles E., Tong, Liang, Kiledjian, Megerditch
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948066/
https://www.ncbi.nlm.nih.gov/pubmed/20802481
http://dx.doi.org/10.1038/nature09338