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The neuronal repellent SLIT2 is a target for repression by EZH2 in prostate cancer

The neuronal repellent SLIT2 is repressed in a number of cancer types primarily through promoter hypermethylation. SLIT2, however, has not been studied in prostate cancer. Through genome-wide location analysis we identified SLIT2 as a target of Polycomb group (PcG) protein EZH2. The EZH2-containing...

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Detalles Bibliográficos
Autores principales: Yu, Jindan, Cao, Qi, Yu, Jianjun, Wu, Longtao, Dallol, Ashraf, Li, James, Chen, Guoan, Grasso, Catherine, Cao, Xuhong, Lonigro, Robert J., Varambally, Sooryanarayana, Mehra, Rohit, Palanisamy, Nallasivam, Wu, Jane Y., Latif, Farida, Chinnaiyan, Arul M.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948081/
https://www.ncbi.nlm.nih.gov/pubmed/20622896
http://dx.doi.org/10.1038/onc.2010.269