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Role of the RNA/DNA kinase Grc3 in transcription termination by RNA polymerase I
Transcription termination by RNA polymerase I in Saccharomyces cerevisiae is mediated by a ‘torpedo' mechanism: co-transcriptional RNA cleavage by Rnt1 at the ribosomal DNA 3′-region generates a 5′-end that is recognized by the 5′–3′ exonuclease Rat1; this degrades the downstream transcript and...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948184/ https://www.ncbi.nlm.nih.gov/pubmed/20814424 http://dx.doi.org/10.1038/embor.2010.130 |