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Aberrant mRNA transcripts and nonsense-mediated decay

Nobody's perfect, and even the cell turns out a certain fraction of erroneous mRNA transcripts. One of the key quality control mechanisms put in place to recognize and eliminate these transcripts before they can be translated into faulty proteins is nonsense-mediated decay. Proteins involved in...

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Detalles Bibliográficos
Autor principal: Trinkle-Mulcahy, Laura
Formato: Texto
Lenguaje:English
Publicado: Biology Reports 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948277/
https://www.ncbi.nlm.nih.gov/pubmed/20948598
http://dx.doi.org/10.3410/B1-93