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Biased agonism
Seven-transmembrane receptors are commonly coupled to multiple signaling pathways in cells. The simple model describing agonists for these receptors as producing a common active state to induce uniform activation of the pathways linked to the receptor has been shown to be untenable in light of a lar...
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Biology Reports Ltd
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948287/ https://www.ncbi.nlm.nih.gov/pubmed/20948603 http://dx.doi.org/10.3410/B1-87 |