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Genetics of pulmonary arterial hypertension: do the molecular findings have translational value?

Pulmonary arterial hypertension (PAH) is usually a devastating condition with a poor prognosis. Nearly 10 years ago, the underlying molecular basis of heritable PAH was elucidated with the identification of mutations in the gene encoding the bone morphogenetic protein type II receptor (BMPR-II). Thi...

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Detalles Bibliográficos
Autor principal: Morrell, Nicholas W
Formato: Texto
Lenguaje:English
Publicado: Faculty of 1000 Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948374/
https://www.ncbi.nlm.nih.gov/pubmed/20948811
http://dx.doi.org/10.3410/B2-22