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l-Arginine deprivation impairs Leishmania major-specific T-cell responses

The amino acid l-arginine plays a crucial role in the regulation of immune responses. We have recently shown that uncontrolled replication of Leishmania parasites at the site of pathology correlates with high levels of arginase activity in nonhealing leishmaniasis and that this elevated arginase act...

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Detalles Bibliográficos
Autores principales: Munder, Markus, Choi, Beak-San, Rogers, Matthew, Kropf, Pascale
Formato: Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948424/
https://www.ncbi.nlm.nih.gov/pubmed/19637195
http://dx.doi.org/10.1002/eji.200839041