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Ganglioside metabolism in a transgenic mouse model of Alzheimer's disease: expression of Chol-1α antigens in the brain

The accumulation of Aβ (amyloid β-protein) is one of the major pathological hallmarks in AD (Alzheimer's disease). Gangliosides, sialic acid-containing glycosphingolipids enriched in the nervous system and frequently used as biomarkers associated with the biochemical pathology of neurological d...

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Detalles Bibliográficos
Autores principales: Ariga, Toshio, Yanagisawa, Makoto, Wakade, Chandramohan, Ando, Susumu, Buccafusco, Jerry J, McDonald, Michael P, Yu, Robert K
Formato: Texto
Lenguaje:English
Publicado: American Society for Neurochemistry 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948441/
https://www.ncbi.nlm.nih.gov/pubmed/20930939
http://dx.doi.org/10.1042/AN20100021