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PP2A Mediated AMPK Inhibition Promotes HSP70 Expression in Heat Shock Response
BACKGROUND: Under stress, AMP-activated protein kinase (AMPK) plays a central role in energy balance, and the heat shock response is a protective mechanism for cell survival. The relationship between AMPK activity and heat shock protein (HSP) expression under stress is unclear. METHODOLOGY/PRINCIPAL...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948495/ https://www.ncbi.nlm.nih.gov/pubmed/20957029 http://dx.doi.org/10.1371/journal.pone.0013096 |