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cDNA Microarray Gene Expression Profiling of Hedgehog Signaling Pathway Inhibition in Human Colon Cancer Cells

BACKGROUND: Hedgehog (HH) signaling plays a critical role in normal cellular processes, in normal mammalian gastrointestinal development and differentiation, and in oncogenesis and maintenance of the malignant phenotype in a variety of human cancers. Increasing evidence further implicates the involv...

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Detalles Bibliográficos
Autores principales: Shi, Ting, Mazumdar, Tapati, DeVecchio, Jennifer, Duan, Zhong-Hui, Agyeman, Akwasi, Aziz, Mohammad, Houghton, Janet A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948497/
https://www.ncbi.nlm.nih.gov/pubmed/20957031
http://dx.doi.org/10.1371/journal.pone.0013054