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Insight into Antigenic Diversity of VAR2CSA-DBL5ε Domain from Multiple Plasmodium falciparum Placental Isolates

BACKGROUND: Protection against pregnancy associated malaria (PAM) is associated with high levels of anti-VAR2CSA antibodies. This protection is obtained by the parity dependent acquisition of anti-VAR2CSA antibodies. Distinct parity-associated molecular signatures have been identified in VAR2CSA dom...

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Detalles Bibliográficos
Autores principales: Gnidehou, Sédami, Jessen, Leon, Gangnard, Stéphane, Ermont, Caroline, Triqui, Choukri, Quiviger, Mickael, Guitard, Juliette, Lund, Ole, Deloron, Philippe, Ndam, Nicaise Tuikue
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948511/
https://www.ncbi.nlm.nih.gov/pubmed/20957045
http://dx.doi.org/10.1371/journal.pone.0013105