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Casein Kinase 2 Dependent Phosphorylation of Neprilysin Regulates Receptor Tyrosine Kinase Signaling to Akt

Neprilysin (NEP) is a type II membrane metalloproteinase that cleaves physiologically active peptides at the cell surface thus regulating the local concentration of these peptides available for receptor binding and signal transduction. In addition, the cytoplasmic N-terminal domain of NEP interacts...

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Detalles Bibliográficos
Autores principales: Siepmann, Martin, Kumar, Sathish, Mayer, Günter, Walter, Jochen
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948513/
https://www.ncbi.nlm.nih.gov/pubmed/20957047
http://dx.doi.org/10.1371/journal.pone.0013134