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Viewing Ageing Eyes: Diverse Sites of Amyloid Beta Accumulation in the Ageing Mouse Retina and the Up-Regulation of Macrophages

BACKGROUND: Amyloid beta (Aβ) accumulates in the ageing central nervous system and is associated with a number of age-related diseases, including age-related macular degeneration (AMD) in the eye. AMD is characterised by accumulation of extracellular deposits called drusen in which Aβ is a key const...

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Detalles Bibliográficos
Autores principales: Hoh Kam, Jaimie, Lenassi, Eva, Jeffery, Glen
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948519/
https://www.ncbi.nlm.nih.gov/pubmed/20957206
http://dx.doi.org/10.1371/journal.pone.0013127