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Glucocorticoid-Induced TNFR-Related (GITR) Protein and Its Ligand in Antitumor Immunity: Functional Role and Therapeutic Modulation

The ability of the tumor necrosis factor receptor (TNFR) family member GITR to modulate immune responses has been the subject of multiple studies. Initially thought to be critically involved in governing functions of regulatory T cells, GITR and its ligand GITRL have meanwhile been found to modulate...

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Detalles Bibliográficos
Autores principales: Placke, Theresa, Kopp, Hans-Georg, Salih, Helmut Rainer
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948872/
https://www.ncbi.nlm.nih.gov/pubmed/20936139
http://dx.doi.org/10.1155/2010/239083