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Mechanistic Studies with DNA Polymerases Reveal Complex Outcomes following Bypass of DNA Damage

DNA is a chemically reactive molecule that is subject to many different covalent modifications from sources that are both endogenous and exogenous in origin. The inherent instability of DNA is a major obstacle to genomic maintenance and contributes in varying degrees to cellular dysfunction and dise...

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Detalles Bibliográficos
Autores principales: Eoff, Robert L., Choi, Jeong-Yun, Guengerich, F. Peter
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948923/
https://www.ncbi.nlm.nih.gov/pubmed/20936119
http://dx.doi.org/10.4061/2010/830473