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Mechanistic Studies with DNA Polymerases Reveal Complex Outcomes following Bypass of DNA Damage
DNA is a chemically reactive molecule that is subject to many different covalent modifications from sources that are both endogenous and exogenous in origin. The inherent instability of DNA is a major obstacle to genomic maintenance and contributes in varying degrees to cellular dysfunction and dise...
Autores principales: | Eoff, Robert L., Choi, Jeong-Yun, Guengerich, F. Peter |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
SAGE-Hindawi Access to Research
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948923/ https://www.ncbi.nlm.nih.gov/pubmed/20936119 http://dx.doi.org/10.4061/2010/830473 |
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