Sulfated Dextrans Enhance In Vitro Amplification of Bovine Spongiform Encephalopathy PrP(Sc) and Enable Ultrasensitive Detection of Bovine PrP(Sc)

BACKGROUND: Prions, infectious agents associated with prion diseases such as Creutzfeldt-Jakob disease in humans, bovine spongiform encephalopathy (BSE) in cattle, and scrapie in sheep and goats, are primarily comprised of PrP(Sc), a protease-resistant misfolded isoform of the cellular prion protein...

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Detalles Bibliográficos
Autores principales: Murayama, Yuichi, Yoshioka, Miyako, Masujin, Kentaro, Okada, Hiroyuki, Iwamaru, Yoshifumi, Imamura, Morikazu, Matsuura, Yuichi, Fukuda, Shigeo, Onoe, Sadao, Yokoyama, Takashi, Mohri, Shirou
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949392/
https://www.ncbi.nlm.nih.gov/pubmed/20957174
http://dx.doi.org/10.1371/journal.pone.0013152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949392/
https://www.ncbi.nlm.nih.gov/pubmed/20957174
http://dx.doi.org/10.1371/journal.pone.0013152

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