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The role of animal models in advancing amyloid-beta immunotherapy to the clinic
The amyloid-beta (Aβ) hypothesis of Alzheimer's disease (AD) causality is now well into its third decade and is finally entering a phase of rigorous clinical testing in numerous late stage clinical trials. The use of Aβ-based animal models of AD has been essential to the discovery and/or precli...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949588/ https://www.ncbi.nlm.nih.gov/pubmed/20682084 http://dx.doi.org/10.1186/alzrt46 |