LPS- induced inflammation exacerbates phospho-tau pathology in rTg4510 mice

Inflammation and microglial activation are associated with Alzheimer's disease (AD) pathology. Somewhat surprisingly, injection of a prototypical inflammatory agent, lipopolysaccharide (LPS) into brains of amyloid precursor protein (APP) transgenic mice clears some of the pre-existing amyloid d...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Daniel C, Rizer, Justin, Selenica, Maj-Linda B, Reid, Patrick, Kraft, Clara, Johnson, Amelia, Blair, Laura, Gordon, Marcia N, Dickey, Chad A, Morgan, Dave
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949628/
https://www.ncbi.nlm.nih.gov/pubmed/20846376
http://dx.doi.org/10.1186/1742-2094-7-56

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949628/
https://www.ncbi.nlm.nih.gov/pubmed/20846376
http://dx.doi.org/10.1186/1742-2094-7-56

Ejemplares similares