Doxorubicin downregulates cell surface B7-H1 expression and upregulates its nuclear expression in breast cancer cells: role of B7-H1 as an anti-apoptotic molecule

INTRODUCTION: B7-H1 (PD-L1, CD274) is a T cell inhibitory molecule expressed in many types of cancer, leading to immune escape of tumor cells. Indeed, in previous reports we have shown an association of B7-H1 expression with high-risk breast cancer patients. METHODS: In the current study, we used im...

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Detalles Bibliográficos
Autores principales: Ghebeh, Hazem, Lehe, Cynthia, Barhoush, Eman, Al-Romaih, Khaldoon, Tulbah, Asma, Al-Alwan, Monther, Hendrayani, Siti-Faujiah, Manogaran, Pulicat, Alaiya, Ayodele, Al-Tweigeri, Taher, Aboussekhra, Abdelilah, Dermime, Said
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949635/
https://www.ncbi.nlm.nih.gov/pubmed/20626886
http://dx.doi.org/10.1186/bcr2605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949635/
https://www.ncbi.nlm.nih.gov/pubmed/20626886
http://dx.doi.org/10.1186/bcr2605

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