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Spatial organization acts on cell signaling: how physical force contributes to the development of cancer
Cells constantly encounter physical forces and respond to neighbors and circulating factors by triggering intracellular signaling cascades that in turn affect their behavior. The mechanisms by which cells transduce mechanical signals to downstream biochemical changes are not well understood. In thei...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949653/ https://www.ncbi.nlm.nih.gov/pubmed/20804566 http://dx.doi.org/10.1186/bcr2623 |