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Suppression of LPS-induced matrix-metalloproteinase responses in macrophages exposed to phenytoin and its metabolite, 5-(p-hydroxyphenyl-), 5-phenylhydantoin

BACKGROUND: Phenytoin (PHT) has been reported to induce gingival (gum) overgrowth (GO) in approximately 50% of patients taking this medication. While most studies have focused on the effects of PHT on the fibroblast in the pathophysiology underlying GO, few studies have investigated the potential re...

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Detalles Bibliográficos
Autores principales: Serra, Ryan, Al-saidi, Abdel-ghany, Angelov, Nikola, Nares, Salvador
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949711/
https://www.ncbi.nlm.nih.gov/pubmed/20843335
http://dx.doi.org/10.1186/1476-9255-7-48