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Suberoylanilide hydroxamic acid induces apoptosis and sub-G1 arrest of 320 HSR colon cancer cells

BACKGROUND: Histone deacetylases and histone acetyl transferases covalently modify histone proteins, consequentially altering chromatin architecture and gene expression. METHODS: The effects of suberoylanilide hydroxamic acid, a HDAC inhibitor, on 320 HSR colon cells were assessed in 320 HSR colon c...

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Detalles Bibliográficos
Autores principales: Sun, Pei-Chang, Tzao, Ching, Chen, Ban-Hen, Liu, Chen-Wei, Yu, Cheng-Ping, Jin, Jong-Shiaw
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949718/
https://www.ncbi.nlm.nih.gov/pubmed/20846458
http://dx.doi.org/10.1186/1423-0127-17-76