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Evaluation of phenoxybenzamine in the CFA model of pain following gene expression studies and connectivity mapping

BACKGROUND: We have previously used the rat 4 day Complete Freund's Adjuvant (CFA) model to screen compounds with potential to reduce osteoarthritic pain. The aim of this study was to identify genes altered in this model of osteoarthritic pain and use this information to infer analgesic potenti...

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Detalles Bibliográficos
Autores principales: Chang, Meiping, Smith, Sarah, Thorpe, Andrew, Barratt, Michael J, Karim, Farzana
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949723/
https://www.ncbi.nlm.nih.gov/pubmed/20846436
http://dx.doi.org/10.1186/1744-8069-6-56