Regulated degradation of the APC coactivator Cdc20

BACKGROUND: Cdc20 is a highly conserved activator of the anaphase-promoting complex (APC), promoting cell-cycle-regulated ubiquitination and proteolysis of a number of critical cell-cycle-regulatory targets including securin and mitotic cyclins. APC-Cdc20 activity is tightly regulated, and this regu...

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Detalles Bibliográficos
Autores principales: Robbins, Jonathan A, Cross, Frederick R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949745/
https://www.ncbi.nlm.nih.gov/pubmed/20831816
http://dx.doi.org/10.1186/1747-1028-5-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949745/
https://www.ncbi.nlm.nih.gov/pubmed/20831816
http://dx.doi.org/10.1186/1747-1028-5-23

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