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The effect of infliximab plus methotrexate on the modulation of inflammatory disease markers in juvenile idiopathic arthritis: analyses from a randomized, placebo-controlled trial

BACKGROUND: We evaluated the effect of infliximab on markers of inflammation in patients with juvenile idiopathic arthritis (JIA). METHODS: In this randomized, placebo-controlled substudy, 122 patients with JIA received infliximab 3 mg/kg + methotrexate (MTX)(n = 60) or placebo + MTX (n = 62) at wee...

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Detalles Bibliográficos
Autores principales: Visvanathan, Sudha, Wagner, Carrie, Marini, Joseph C, Lovell, Daniel J, Martini, Alberto, Petty, Ross, Cuttica, Ruben, Woo, Patricia, Espada, Graciela, Gattorno, Marco, Apaz, Maria T, Baildam, Eileen, Fasth, Anders, Gerloni, Valeria, Lahdenne, Pekka, Quartier, Pierre, Saurenmann, Rotraud, Travers, Suzanne, Mendelsohn, Alan, Xu, Stephen, Giannini, Edward H, Ruperto, Nicolino
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949752/
https://www.ncbi.nlm.nih.gov/pubmed/20822542
http://dx.doi.org/10.1186/1546-0096-8-24