Polymorphisms in folate-metabolizing genes, chromosome damage, and risk of Down syndrome in Italian women: identification of key factors using artificial neural networks

BACKGROUND: Studies in mothers of Down syndrome individuals (MDS) point to a role for polymorphisms in folate metabolic genes in increasing chromosome damage and maternal risk for a Down syndrome (DS) pregnancy, suggesting complex gene-gene interactions. This study aimed to analyze a dataset of gene...

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Detalles Bibliográficos
Autores principales: Coppedè, Fabio, Grossi, Enzo, Migheli, Francesca, Migliore, Lucia
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949778/
https://www.ncbi.nlm.nih.gov/pubmed/20868477
http://dx.doi.org/10.1186/1755-8794-3-42

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949778/
https://www.ncbi.nlm.nih.gov/pubmed/20868477
http://dx.doi.org/10.1186/1755-8794-3-42

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