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Polymorphisms in folate-metabolizing genes, chromosome damage, and risk of Down syndrome in Italian women: identification of key factors using artificial neural networks
BACKGROUND: Studies in mothers of Down syndrome individuals (MDS) point to a role for polymorphisms in folate metabolic genes in increasing chromosome damage and maternal risk for a Down syndrome (DS) pregnancy, suggesting complex gene-gene interactions. This study aimed to analyze a dataset of gene...
Autores principales: | Coppedè, Fabio, Grossi, Enzo, Migheli, Francesca, Migliore, Lucia |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949778/ https://www.ncbi.nlm.nih.gov/pubmed/20868477 http://dx.doi.org/10.1186/1755-8794-3-42 |
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