Phosphorylation of HOX11/TLX1 on Threonine-247 during mitosis modulates expression of cyclin B1

BACKGROUND: The HOX11/TLX1 (hereafter referred to as HOX11) homeobox gene was originally identified at a t(10;14)(q24;q11) translocation breakpoint, a chromosomal abnormality observed in 5-7% of T cell acute lymphoblastic leukemias (T-ALLs). We previously reported a predisposition to aberrant spindl...

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Detalles Bibliográficos
Autores principales: Chen, Edwin, Huang, Xiaoyong, Zheng, Yanzhen, Li, You-Jun, Chesney, Alden, Ben-David, Yaacov, Yang, Eric, Hough, Margaret R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949800/
https://www.ncbi.nlm.nih.gov/pubmed/20846384
http://dx.doi.org/10.1186/1476-4598-9-246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949800/
https://www.ncbi.nlm.nih.gov/pubmed/20846384
http://dx.doi.org/10.1186/1476-4598-9-246

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